SkQ1 SKULACEV ION
Mechanism of action:
Antioxidant SkQ (Skulachev Ion) has the unique ability to penetrate and accumulate in the mitochondria of cells - the exact site of free radical formation - neutralizing free radicals as they form and maintaining the healthy functioning of the cell and its parts. It is precisely due to the ability to penetrate mitochondria (and accumulate) that the proven effectiveness of the SkQ antioxidant is many times higher than other antioxidants.
The positive effect of SkQ is associated with its following properties: penetration into the mitochondria — the main source of reactive oxygen species (ROS) of the cells inhibition of ROS at the site of their formation in two different ways: direct neutralization of ROS due to the oxidation of plastoquinone, reduction of mitochondrial membrane potential.
Unlike the most of conventional drugs, SkQ is capable of treating a variety of seemingly different disorders across all therapeutic areas. SkQ1 has been shown to be effective in animal models of many conditions attributable to ageing process from ophthalmology to neurodegeneration and CV disorders:
- SkQ1 showed a pronounced anti-inflammatory effect.
- SkQ is able to delay the development of several traits of aging and increase the life span in a variety of animals.
- It was shown that SkQ accelerates wound healing, as well as treats age-related diseases such as osteoporosis, cataracts, retinopathy and others.
- The drug "Visomitin" on the basis of SkQ1 used in veterinary practice for the treatment of ophthalmologic diseases in pets. In particular, the effectiveness is shown for the treatment of retinopathy in dogs, cats and horses.
- Experiments have shown an unexpected effect of SkQ on plants. The substance stimulated differentiation (in the treatment of callus) and seed germination (patent US 8,557,733), increased the yield of different crops.
SkQ1 is included in the composition of cosmetic products such as Mitovitan Active, Mitovitan serum and Exomitin.
Skulachev Ion SkQ in WIKIPEDIA:
SkQ Skulachev Ion is a class of mitochondria-targeted antioxidants, developed by Professor Vladimir Skulachev and his team. In a broad sense, SkQ is a lipophilic cation, linked via saturated hydrocarbon chain to an antioxidant. Due to its lipophilic properties, SkQ can effectively penetrate through various cell membranes. The positive charge provides directed transport of the whole molecule including antioxidant moiety into the negatively charged mitochondrial matrix. Read more
Research:
The research was conducted by Vladimir Petrovich Skulachev, a biochemist, academician of the Russian Academy of Sciences, dean of the Faculty of Bioengineering and Bioinformatics of Moscow State University, which he founded in 2002 and led it until 02.2023. His team consists of about 100 specialists.
THE PRODUCTS ARE NOT A MEDICINES
Mitotech
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